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“An analogue of tetrahydrocannabinol (THC) with antiemetic, anxiolytic, appetite-stimulating, analgesic, and neuroprotective properties. [Delta-8-THC] binds to the cannabinoid G-protein coupled receptor CB1, located in the central nervous system…This agent exhibits a lower psychotropic potency than [delta-9-THC], the primary form of THC found in cannabis.” (https://www.cancer.gov/publications/dictionaries/cancer-drug/def/delta-8-tetrahydrocannabinol?redirect=true)
Delta-8-THC is chemically different from delta-9-THC by only a few atomic bonds and still offers a potent high of its own. However, delta-8-tetrahydrocannabinol has a lower psychotropic potency than its close cousin delta-9 THC. Consumers have noted many positive effects with delta – 8 including: relaxation, happy, uplifting, euphoric, complete body high, appetite stimulation, feeling a head high (stoned), and nausea relief.
Delta-8-THC binds to the CB1 receptors located in the central nervous system. Delta-8-THC additionally has an affinity for CB2 receptors, although less is known about this binding mechanism. (https://pubchem.ncbi.nlm.nih.gov/compound/delta8-Tetrahydrocannabinol).